Endonasal endoscopic resection and radiotherapy in olfactory neuroblastoma: our experience.

Abstract

BACKGROUND:

Our aim was to evaluate the efficacy of a bimodal method of treatment consisting in endoscopic resection followed by radiotherapy in patients with olfactory neuroblastoma (ON).

METHODS:

This is a retrospective review on 10 patients with ON treated at a tertiary referral center. All the patients were treated with endonasal endoscopic resection, and 1 refused postoperative radiotherapy.

RESULTS:

No mortality was observed. Local tumor control was obtained in all the patients. Follow-up ranged from 15 to 79 months (median, 37 months). One patient developed a regional recurrence and for this was treated with bilateral, modified type III radical neck dissection plus radiotherapy on the neck. All patients regained a good quality of life after the treatment.

CONCLUSIONS:

This method of treatment causes minimal injury to the patients, reduces side effects, and improves the quality of life of those with olfactory neuroblastoma.

• Authors: Paolo Castelnuovo, Maurizio Bignami, Giovanni Delù, Paolo Battaglia, Mario Bignardi, Iacopo Dallan
• Journal: Head & neck (Head Neck) Vol. 29 Issue 9 Pg. 845-50 (Sep 2007) ISSN: 1043-3074 [Print] United States
• PMID: 17427966 (Publication Type: Journal Article)
• Copyright: (c) 2007 Wiley Periodicals, Inc. Head Neck, 2007.

Topics

• Adolescent
• Adult
• Aged
• Endoscopy (methods)
• Esthesioneuroblastoma, Olfactory (radiotherapy, surgery)
• Humans
• Magnetic Resonance Imaging
• Male
• Middle Aged
• Nasal Cavity
• Nose Neoplasms (radiotherapy, surgery)
• Quality of Life
• Radiotherapy, Adjuvant
• Retrospective Studies