| Abstract | Facial transplantation has long captured the interest and imagination of scientists, the media, and the lay public. Facial transplantation could provide an excellent alternative to current treatments for facial disfigurement caused by burns, trauma, cancer extirpation, or congenital birth defects. This article discusses the major technical, immunologic, psychosocial and ethical hurdles that have been overcome to bring facial transplantation from an idea to a clinical reality by providing the reader with a chronologic overview of the research and events that have led this exciting new treatment into the clinical arena. |
| Authors | John H Barker, Niki Stamos, Allen Furr, Sean McGuire, Michael Cunningham, Osborne Wiggins, Charles S Brown, Brian Gander, Claudio Maldonado, Joseph C Banis Jr
(Affiliation: Department of Surgery, 511 South Floyd Street, 320 MDR Building, University of Louisville, Louisville, KY 40202, USA. jhbark01 at louisville.edu)
|
| Journal | Clinics in plastic surgery
(Clin Plast Surg)
Vol. 34
Issue 2
Pg. 233-50, ix
(Apr 2007)
ISSN: 0094-1298 United States |
| PMID | 17418674
(Publication Type: Historical Article, Journal Article, Research Support, Non-U.S. Gov't, Review)
|
| Chemical References |
|
| Topics |
- Acute Disease
- Ethics, Clinical
- Facial Injuries
(surgery)
- Graft Rejection
(prevention & control)
- History, 20th Century
- History, 21st Century
- Host vs Graft Reaction
- Humans
- Immunosuppressive Agents
(therapeutic use)
- Reconstructive Surgical Procedures
(history, methods)
- Transplantation, Homologous
(history, methods)
|