Abstract | UNLABELLED: STUDY OBJECTIVE: DESIGN, SETTING, PARTICIPANTS: Cross-sectional study, including the enrollment of participants, ages 8 to 20 years, recruited from the pediatric endocrinology clinical program of a tertiary pediatric referral center. INTERVENTIONS: Ten participants had oral glucose tolerance testing, adrenal and ovarian androgen measurements, and pelvic ultrasound studies performed. MAIN OUTCOME MEASURES: Presence of altered response to glucose challenge, ovarian hyperandrogenism, or presence of polycystic ovaries by ultrasound. RESULTS: CONCLUSIONS: Females with classic congenital adrenal hyperplasia (21-hydroxylase deficiency) and normal glucose tolerance appear to have normal ovarian structure and function during the peripubertal period.
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Authors | Amy Fleischman, Harriet Paltiel, Jeanne Chow, Julie Ringelheim, Catherine M Gordon |
Journal | Journal of pediatric and adolescent gynecology
(J Pediatr Adolesc Gynecol)
Vol. 20
Issue 2
Pg. 67-72
(Apr 2007)
ISSN: 1083-3188 [Print] United States |
PMID | 17418389
(Publication Type: Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Adolescent
- Adrenal Hyperplasia, Congenital
(drug therapy, physiopathology)
- Adult
- Child
- Cross-Sectional Studies
- Female
- Glucocorticoids
(therapeutic use)
- Glucose Tolerance Test
- Humans
- Ovarian Function Tests
- Ovary
(anatomy & histology, physiology)
- Statistics, Nonparametric
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