Abstract | BACKGROUND: METHODS: RESULTS: CONCLUSIONS: These data identify a complex role for MMPs and TIMPs in the immunopathogenesis of lung allograft rejection, and indicate their effects are not limited to matrix remodeling.
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Authors | Shigetoshi Yoshida, Takekazu Iwata, Masako Chiyo, Gerald N Smith, Brian H Foresman, Elizabeth A Mickler, Kathleen M Heidler, Oscar W Cummings, Takehiko Fujisawa, David D Brand, Andrew Baker, David S Wilkes |
Journal | Transplantation
(Transplantation)
Vol. 83
Issue 6
Pg. 799-808
(Mar 27 2007)
ISSN: 0041-1337 [Print] United States |
PMID | 17414715
(Publication Type: Journal Article, Research Support, N.I.H., Extramural)
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Chemical References |
- Collagen Type V
- Interleukin-1beta
- Matrix Metalloproteinase Inhibitors
- Tetracyclines
- Tissue Inhibitor of Metalloproteinase-1
- Tumor Necrosis Factor-alpha
- tetracycline CMT-3
- Tissue Inhibitor of Metalloproteinase-2
- Matrix Metalloproteinases
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Topics |
- Animals
- Autoimmunity
(immunology, physiology)
- Collagen Type V
(immunology)
- Graft Rejection
(immunology, pathology)
- Hypersensitivity, Delayed
(immunology, physiopathology)
- Interleukin-1beta
(metabolism)
- Lung Transplantation
(immunology, pathology)
- Male
- Matrix Metalloproteinase Inhibitors
- Matrix Metalloproteinases
(physiology)
- Rats
- Rats, Inbred F344
- Rats, Wistar
- Tetracyclines
(pharmacology)
- Tissue Inhibitor of Metalloproteinase-1
(physiology)
- Tissue Inhibitor of Metalloproteinase-2
(physiology)
- Transplantation, Homologous
(immunology, physiology)
- Tumor Necrosis Factor-alpha
(metabolism)
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