| Abstract | We report a patient with very advanced myelofibrosis and huge splenomegaly who showed a complete hematological response to low dose thalidomide with reversal of splenomegaly and bone narrow fibrosis after 30 months of the treatment. |
| Authors | Alain Berrebi, Edit Feldberg, Irena Spivak, Lev Shvidel
(Affiliation: Hematology Institute, Kaplan Medical Center, Rehovot, Israel 76100. alain_b at clalit.org.il)
|
| Journal | Haematologica
(Haematologica)
Vol. 92
Issue 2
Pg. e15-6
(Feb 2007)
ISSN: 1592-8721 Italy |
| PMID | 17405746
(Publication Type: Case Reports, Journal Article)
|
| Chemical References |
- Angiogenesis Inhibitors
- Vitamin B Complex
- Thalidomide
- Prednisone
- Folic Acid
- Fluoxymesterone
|
| Topics |
- Aged, 80 and over
- Angiogenesis Inhibitors
(administration & dosage, therapeutic use)
- Blood Transfusion
- Bone Marrow
(pathology)
- Combined Modality Therapy
- Drug Therapy, Combination
- Fluoxymesterone
(administration & dosage, therapeutic use)
- Folic Acid
(administration & dosage, therapeutic use)
- Humans
- Male
- Myelofibrosis
(complications, drug therapy, pathology, therapy)
- Prednisone
(administration & dosage, therapeutic use)
- Remission Induction
- Splenomegaly
(etiology)
- Thalidomide
(administration & dosage, therapeutic use)
- Vitamin B Complex
(administration & dosage, therapeutic use)
|