HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Surgery on neuroendocrine tumours.

Abstract
Neuroendocrine tumours of the gastrointestinal tract and pancreas present a major challenge to physicians in their recognition and treatment requirements, and surgical treatment of these tumours has become increasingly important for symptom palliation and survival. For some carcinoid tumours the extent of surgery may depend on tumour size. Midgut carcinoid is the most common cause of the carcinoid syndrome, requiring surgery for primary and mesenteric tumours to minimize the risk for abdominal complications but also for removal of liver metastases to palliate hormonal symptoms. Among endocrine pancreatic tumours, insulinoma and gastrinoma often cause severe symptoms of hormone excess despite their inconspicuous size, but they can be successfully removed with improved pre- and intraoperative localization. Other tumours--glucagonoma, VIPoma, and non-functioning endocrine pancreatic tumours--are often large or metastasizing, but generally require surgical debulking to alleviate hormonal symptoms and have favourable survival.
AuthorsGöran Akerström, Per Hellman
JournalBest practice & research. Clinical endocrinology & metabolism (Best Pract Res Clin Endocrinol Metab) Vol. 21 Issue 1 Pg. 87-109 (Mar 2007) ISSN: 1521-690X [Print] Netherlands
PMID17382267 (Publication Type: Journal Article, Review)
Topics
  • Algorithms
  • Carcinoid Tumor (pathology, surgery)
  • Gastrinoma (surgery)
  • Glucagonoma (surgery)
  • Humans
  • Insulinoma (surgery)
  • Intestinal Neoplasms (surgery)
  • Liver Neoplasms (secondary, surgery)
  • Models, Biological
  • Multiple Endocrine Neoplasia Type 1 (complications, surgery)
  • Nesidioblastosis (surgery)
  • Neuroendocrine Tumors (complications, pathology, surgery)
  • Pancreatic Neoplasms (complications, pathology, surgery)
  • Stomach Neoplasms (surgery)
  • Vipoma (surgery)
  • Zollinger-Ellison Syndrome (surgery)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: