Abstract | OBJECTIVES: To determine the prevalence of impaired detrusor contractility (IDC) with and without detrusor hyperactivity (DH) among community-dwelling elderly with lower urinary tract symptoms and to identify which patients are at a greater risk of having a hypocontractile detrusor. METHODS: We performed a retrospective chart review of all patients 70 years old or older with storage and/or voiding lower urinary tract symptoms who had undergone urodynamic pressure-flow studies in a urodynamic referral center during a 2-year period. RESULTS: During the study period, 181 patients (82 men [45%] and 99 women [55%]), aged 70 years or older (mean age 75.7 +/- 4.8), underwent urodynamic studies. IDC was detected in 39 (48%) of the 82 men and in 12 (12%) of the 99 women. Two thirds of the men and one half of the women with IDC also had involuntary detrusor contractions during the filling phase and/or low bladder compliance. The prevalence of IDC/DH-IDC was significantly greater in those with a history of urinary retention and an indwelling urethral catheter. CONCLUSIONS: Detrusor-impaired contractility is an important pathophysiologic mechanism in older patients with lower urinary tract symptoms, especially in men. Establishing the diagnosis by urodynamic pressure-flow studies is crucial for determining treatment--potentially harmful to this vulnerable population--from objective parameters rather than by empirical decisions.
|
Authors | Joseph Abarbanel, Esther-Lee Marcus |
Journal | Urology
(Urology)
Vol. 69
Issue 3
Pg. 436-40
(Mar 2007)
ISSN: 1527-9995 [Electronic] United States |
PMID | 17382138
(Publication Type: Journal Article)
|
Topics |
- Aged
- Aged, 80 and over
- Female
- Humans
- Male
- Muscle Contraction
(physiology)
- Retrospective Studies
- Urinary Bladder
(physiopathology)
- Urinary Bladder, Overactive
(physiopathology)
- Urination Disorders
(physiopathology)
- Urodynamics
|