Acanthamoeba keratitis related to orthokeratology.

Abstract

PURPOSE:

To report four cases of Acanthamoeba keratitis related to the overnight wearing of orthokeratology lenses.

METHODS:

Four patients had histories of overnight wearing of orthokeratology lenses when they presented with corneal ulcers. They had used a contact lens care system irregularly with tap water.

RESULTS:

The organism isolated by corneal scraping was Acanthamoeba. The patients were treated with polyhexamethylene biguanide (PHMB) and chlorhexidine, resulting in a resolution of ocular inflammation.

CONCLUSION:

The risk of Acanthamoeba keratitis as a potential complication of overnight orthokeratology should be considered, especially in patients with over one-year duration of contact lens wearing. Careful contact lens management is needed and tap-water rinsing should be eliminated from the lens care regimen.

• Authors: Ji-Eun Lee, Tae Won Hahn, Boo Sup Oum, Hee Young Choi, Hak Sun Yu, Jong Soo Lee
• Journal: International ophthalmology (Int Ophthalmol) Vol. 27 Issue 1 Pg. 45-9 (Feb 2007) ISSN: 0165-5701 [Print] Netherlands
• PMID: 17377749 (Publication Type: Case Reports, Journal Article)

Chemical References

• Anti-Infective Agents, Local
• Biguanides
• polihexanide
• Chlorhexidine

Topics

• Acanthamoeba Keratitis (drug therapy, etiology, pathology, physiopathology)
• Adolescent
• Anti-Infective Agents, Local (therapeutic use)
• Biguanides (therapeutic use)
• Chlorhexidine (therapeutic use)
• Circadian Rhythm
• Contact Lenses (adverse effects)
• Drug Therapy, Combination
• Female
• Humans
• Male
• Visual Acuity