Abstract | OBJECTIVE: METHODS: RESULTS: (1) Lung pathobiology fibrosis were alleviated was alleviated significantly in Qidan granule group compared with those in model group and hydrocortisone group (p < 0.01). (2) In Qidan group and hydrocortisone group, the expression of TGF-beta(1) protein was 1.71 +/- 0.17 and 1, 78 +/- 0.17 in day 28 group and day 42 group, respectively. The expression of TNF-aprotein was 2.16 +/- 0.40 and 1.98 +/- 0.33 in day 28 group and day 42 group, respectively. The expression of TGF-beta(1) and TNF-alpha protein was significantly difference from those in the model group and the hydrocortisone group (p < 0.01). CONCLUSIONS:
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Authors | Chang-Jun Jin, Hong-Tao Xin, Dian-Jie Lin, Zhen Wang |
Journal | Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases
(Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi)
Vol. 25
Issue 1
Pg. 22-5
(Jan 2007)
ISSN: 1001-9391 [Print] China |
PMID | 17374183
(Publication Type: English Abstract, Journal Article, Research Support, U.S. Gov't, Non-P.H.S.)
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Chemical References |
- Drugs, Chinese Herbal
- Transforming Growth Factor beta
- Tumor Necrosis Factor-alpha
- qidan
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Topics |
- Animals
- Drugs, Chinese Herbal
(therapeutic use)
- Lung
(metabolism, pathology)
- Male
- Phytotherapy
- Pulmonary Fibrosis
(drug therapy, metabolism, pathology)
- Rats
- Rats, Sprague-Dawley
- Transforming Growth Factor beta
(metabolism)
- Tumor Necrosis Factor-alpha
(metabolism)
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