[Surgical treatment of refractory hyperparathyroidism and usefulness of the intraoperative PTH]

• Abstract: OBJECTIVE: To share our experience in the surgery of so-called refractory hyperparathyroidism (secondary and tertiary without response to therapy with calcitriol). MATERIAL AND METHODS: Retrospective study based on 41 patients-5 with secondary and 6 with tertiary hyperparathyroidism-referred by nephrology for surgical evaluation of their illness because of poor response to the medical treatment given. RESULTS: In 18 of the 41 cases we used the fast or turbo intra-operative PTH with reduction of more than 60 % in all patients. In the group in whom normal PTH was performed, we registered 2 secondary hyperparathyroidisms with no significant decrease and persistence of symptoms. One of them was reoperated successfully. DISCUSSION: Subtotal or total parathyroidectomy with reimplant represents the treatment of choice in refractory hyperparathyroidism with good results in most of the series reviewed.
• Authors: Vicente Pino Rivero, Alicia González Palomino, Carlos G Pantoja Hernández, María Elena Mora Santos, Mercedes Guerra Camacho, Fernando Carrasco Claver, Gonzalo Barrantes Celaya (Affiliation: Servicio de Otorrinolaringología, Complejo Hospitalario Infanta Cristina, Badajoz, España. vicentepinorivero at terra.com)
• Journal: Acta otorrinolaringológica española (Acta Otorrinolaringol Esp) Vol. 58 Issue 2 Pg. 39-42 (Feb 2007) ISSN: 0001-6519 [Print] Spain
• Vernacular Title: Tratamiento quirúrgico del hiperparatiroidismo refractario y utilidad de la paratirina intraoperatoria.
• PMID: 17371679 (Publication Type: English Abstract, Journal Article)

Chemical References

• Parathyroid Hormone
• Calcium

Topics

• Adult
• Aged
• Calcium (blood)
• Female
• Humans
• Hyperparathyroidism, Secondary (blood, surgery)
• Intraoperative Care
• Male
• Middle Aged
• Parathyroid Hormone (blood)
• Parathyroidectomy (methods)
• Reoperation (statistics & numerical data)
• Retrospective Studies