[Surgical treatment of refractory hyperparathyroidism and usefulness of the intraoperative PTH].

To share our experience in the surgery of so-called refractory hyperparathyroidism (secondary and tertiary without response to therapy with calcitriol).
Retrospective study based on 41 patients-5 with secondary and 6 with tertiary hyperparathyroidism-referred by nephrology for surgical evaluation of their illness because of poor response to the medical treatment given.
In 18 of the 41 cases we used the fast or turbo intra-operative PTH with reduction of more than 60 % in all patients. In the group in whom normal PTH was performed, we registered 2 secondary hyperparathyroidisms with no significant decrease and persistence of symptoms. One of them was reoperated successfully.
Subtotal or total parathyroidectomy with reimplant represents the treatment of choice in refractory hyperparathyroidism with good results in most of the series reviewed.
AuthorsVicente Pino Rivero, Alicia González Palomino, Carlos G Pantoja Hernández, María Elena Mora Santos, Mercedes Guerra Camacho, Fernando Carrasco Claver, Gonzalo Barrantes Celaya
JournalActa otorrinolaringoloĢgica espanĢƒola (Acta Otorrinolaringol Esp) Vol. 58 Issue 2 Pg. 39-42 (Feb 2007) ISSN: 0001-6519 [Print] Spain
Vernacular TitleTratamiento quirúrgico del hiperparatiroidismo refractario y utilidad de la paratirina intraoperatoria.
PMID17371679 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Parathyroid Hormone
  • Calcium
  • Adult
  • Aged
  • Calcium (blood)
  • Female
  • Humans
  • Hyperparathyroidism, Secondary (blood, surgery)
  • Intraoperative Care
  • Male
  • Middle Aged
  • Parathyroid Hormone (blood)
  • Parathyroidectomy (methods)
  • Reoperation (statistics & numerical data)
  • Retrospective Studies

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