Abstract | BACKGROUND: OBSERVATIONS: A child with X-linked severe combined immunodeficiency disease developed multiple renal and pulmonary leiomyomata 8 years after haploidentical BMT. Epstein-Barr viral DNA was detectable in the blood and in situ hybridization for EBV-encoded RNAs was positive in the tumor. The tumors have been radiographically stable, chimerism remains mixed, and plasma EBV DNA has been repeatedly negative for over 2 years after donor lymphocyte infusion. CONCLUSIONS:
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Authors | Srilatha Atluri, Kathleen Neville, Mary Davis, Kent A Robertson, Francis E Marshalleck, Dennis P O'Malley, Rebecca H Buckley, Robert P Nelson Jr |
Journal | Journal of pediatric hematology/oncology
(J Pediatr Hematol Oncol)
Vol. 29
Issue 3
Pg. 166-72
(Mar 2007)
ISSN: 1077-4114 [Print] United States |
PMID | 17356396
(Publication Type: Case Reports, Journal Article)
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Topics |
- Bone Marrow Transplantation
(adverse effects, immunology)
- Child
- Chimerism
- Epstein-Barr Virus Infections
(complications, pathology)
- Humans
- Kidney Neoplasms
(diagnosis, virology)
- Leiomyomatosis
(pathology, virology)
- Lung Neoplasms
(diagnosis, virology)
- Male
- Sensitivity and Specificity
- Severe Combined Immunodeficiency
(immunology, therapy, virology)
- T-Lymphocytes
(pathology, virology)
- Tomography, X-Ray Computed
(methods)
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