HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

[Transient complete AV block as a sequela of Borrelia myocarditis].

Abstract
A 49-year-old man suddenly developed dyspnoea, sweating, fever (up to 38.5 degrees C), vertigo and angina. After emergency admittance to hospital the ECG showed 3 degrees A-V block, requiring temporary pacemaker insertion. The patient reported that a month before he had been bitten, probably by a tick. Serological tests demonstrated a recent Borrelia infection (rise of IgG antibody titre to 1:2048, IgM antibody titre to 1:128). Coronary angiography excluded any haemodynamically significant coronary heart disease as a cause of the conduction disorder. Myocardial biopsy showed changes pointing to a past myocarditis. This suggested Borrelia infection as the cause of the complete A-V block. Under treatment with broad-spectrum antibiotics for 15 days the fever subsided and the ECG became normal. Shortly before discharge, an elevated pulmonary wedge pressure on 150 W exercise indicated persistence of mild left-ventricular failure.
AuthorsK M Kruse, R Gust, W Grosse-Heitmeyer
JournalDeutsche medizinische Wochenschrift (1946) (Dtsch Med Wochenschr) Vol. 117 Issue 5 Pg. 167-71 (Jan 31 1992) ISSN: 0012-0472 [Print] Germany
Vernacular TitlePassagere komplette AV-Blockierung als Folge einer Borrelienmyokarditis.
PMID1735375 (Publication Type: Case Reports, English Abstract, Journal Article)
Chemical References
  • Antibodies, Bacterial
Topics
  • Antibodies, Bacterial (blood)
  • Borrelia burgdorferi Group (immunology)
  • Cardiac Catheterization
  • Drug Therapy, Combination
  • Electrocardiography
  • Heart Block (diagnosis, etiology, therapy)
  • Humans
  • Lyme Disease (complications, diagnosis, therapy)
  • Male
  • Middle Aged
  • Myocarditis (complications, diagnosis, therapy)
  • Pacemaker, Artificial

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: