HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

The use of fractional laser photothermolysis for the treatment of atrophic scars.

AbstractBACKGROUND:
Patients with atrophic scars commonly seek treatment for their removal but are often concerned about the prolonged recovery, short-lived results, and/or ineffectiveness of available therapies. A novel treatment using a 1,550-nm erbium-doped fiber laser to induce fractional photothermolysis of treated skin has been used to resurface photodamaged skin but has not been studied previously in patients with atrophic scars to determine its effectiveness for this condition.
PURPOSE:
To determine the effectiveness and safety of 1,550-nm erbium-doped fiber laser treatment on atrophic scars.
METHODS:
Fifty-three patients (skin phototypes I-V) with mild to moderate atrophic facial acne scars received monthly treatment with a 1,550-nm erbium-doped fiber laser (Fraxel, Reliant Technologies Inc., San Diego, CA). Clinical response to treatment was determined at each treatment visit and 6 months after the final treatment session by two independent assessors using a quartile grading scale. Side effects and patient satisfaction were monitored at each follow-up visit.
RESULTS:
Clinical improvement averaged 51% to 75% in nearly 90% of patients after three monthly laser treatments. Mean improvement scores increased proportionately with each successive laser session. Clinical response rates were independent of age, gender, or skin phototype. Side effects included transient erythema and edema in most patients, but no dyspigmentation, ulceration, or scarring.
CONCLUSIONS:
Atrophic scars can be effectively and safely reduced with 1,550-nm erbium-doped fiber laser treatment.
AuthorsTina S Alster, Elizabeth L Tanzi, Melissa Lazarus
JournalDermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] (Dermatol Surg) Vol. 33 Issue 3 Pg. 295-9 (Mar 2007) ISSN: 1076-0512 [Print] United States
PMID17338686 (Publication Type: Journal Article)
Topics
  • Acne Vulgaris (complications)
  • Adult
  • Aged
  • Cicatrix (etiology, pathology, therapy)
  • Dose Fractionation, Radiation
  • Female
  • Humans
  • Laser Therapy
  • Male
  • Middle Aged
  • Phototherapy (methods)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: