Zollinger Ellison syndrome, treated with lansoprazole, during pregnancy.

Zollinger Ellison syndrome (ZES), an ulcerative disease of the upper gastrointestinal tract that involves the production of high levels of gastrin and gastric acid, is a rare, symptomatic, endocrine neoplastic disease.
We report a rare case of gastrinoma that was first diagnosed during pregnancy in which the primary tumor was located in the liver. The ZES was well controlled with Zoton (Lansoprazole) following surgery. The patient had an uneventful pregnancy and delivery without significant complications.
The present case suggests that treatment with Zoton for ZES during pregnancy is safe and effective.
AuthorsAmit Mayer, Eyal Sheiner, Gershon Holcberg
JournalArchives of gynecology and obstetrics (Arch Gynecol Obstet) Vol. 276 Issue 2 Pg. 171-3 (Aug 2007) ISSN: 0932-0067 [Print] Germany
PMID17318560 (Publication Type: Case Reports, Journal Article)
Chemical References
  • 2-Pyridinylmethylsulfinylbenzimidazoles
  • Anti-Ulcer Agents
  • Gastrins
  • Lansoprazole
  • 2-Pyridinylmethylsulfinylbenzimidazoles (therapeutic use)
  • Adult
  • Anti-Ulcer Agents (therapeutic use)
  • Female
  • Gastrinoma (complications, drug therapy, pathology, surgery)
  • Gastrins (blood)
  • Humans
  • Infant, Newborn
  • Lansoprazole
  • Male
  • Pregnancy
  • Pregnancy Complications, Neoplastic (blood, drug therapy, surgery)
  • Pregnancy Outcome
  • Zollinger-Ellison Syndrome (blood, complications, drug therapy, surgery)

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