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Differential expression of selected gene products in uterine leiomyomata and adenomyosis.

Abstract
Gene products estrogen receptor alpha, progesterone receptor-A, retinoid X receptor alpha, insulin-like growth factor-II, insulin-like growth factor I receptor beta, platelet-derived growth factor, epithelial growth factor receptor, and BCL-2 were examined by immunohistochemistry with the aid of a tissue microarray from 46 hysterectomies with adenomyosis and leiomyomata. With appropriate internal controls, there were significant differences in gene expression between adenomyosis and leiomyomata.
AuthorsMary Levy, Khush Mittal, Luis Chiriboga, Xinmin Zhang, Herman Yee, Jian-Jun Wei
JournalFertility and sterility (Fertil Steril) Vol. 88 Issue 1 Pg. 220-3 (Jul 2007) ISSN: 1556-5653 [Electronic] United States
PMID17296180 (Publication Type: Comparative Study, Journal Article)
Chemical References
  • Genetic Markers
Topics
  • Adult
  • Endometriosis (genetics, metabolism)
  • Female
  • Gene Expression Profiling
  • Genetic Markers (genetics)
  • Humans
  • Immunohistochemistry
  • Leiomyomatosis (genetics, metabolism)
  • Middle Aged

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