| Abstract | Desmoid tumor (aggressive fibromatosis), as a member of a group of borderline neoplasms, is a rare tumor of fibroblastic origin that remains difficult to treat. Treatments with surgery, radiotherapy and different medical protocols including interferon (IFN)-alpha, hormonal agents such as tamoxifen (anti-estrogen) as well as non-steroidal anti-inflammatory drugs and low-dose antineoplastic agents have been reported. In this report we describe a new patient with multifocal aggressive fibromatosis who was successfully treated with low-dose chemotherapy consisting of methotrexate and vinblastine. |
| Authors | Kudret Caglar, Hasan Ozyönüm, Minel Akalin, Sevim Balci
(Affiliation: Pediatric Oncology Unit, Dr. Burhan Nalbantoglu State Hospital, Nicosia, North Cyprus.)
|
| Journal | The Turkish journal of pediatrics
(Turk J Pediatr)
2006 Oct-Dec
Vol. 48
Issue 4
Pg. 365-8
ISSN: 0041-4301 Turkey |
| PMID | 17290575
(Publication Type: Case Reports, Journal Article)
|
| Chemical References |
- Antimetabolites, Antineoplastic
- Methotrexate
- Vinblastine
|
| Topics |
- Adolescent
- Antimetabolites, Antineoplastic
(administration & dosage, therapeutic use)
- Antineoplastic Combined Chemotherapy Protocols
(administration & dosage, therapeutic use)
- Biopsy
- Female
- Fibromatosis, Aggressive
(drug therapy, pathology)
- Follow-Up Studies
- Humans
- Methotrexate
(administration & dosage, therapeutic use)
- Time Factors
- Treatment Outcome
- Vinblastine
(administration & dosage, therapeutic use)
|
