Vitamin E and selenium supplementation reduces plasma cortisol and oxidative stress in dystocia-affected buffaloes.

Abstract

The aim of the study was to evaluate oxidative stress around parturition in normally calved and dystocia-affected buffaloes and the clinical efficacy of vitamin E and selenium (Se) in reducing the effects in buffaloes suffering from dystocia. Plasma cortisol concentration, erythrocytic malondialdehyde (MDA) level and superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) activities were evaluated in dystocia-affected (supplemented (n = 8) and unsupplemented (n = 5) with vitamin E and Se) and normally calved (unsupplemented; n = 6) buffaloes. The decline in plasma cortisol concentration, MDA level and SOD activity was greater in the group of dystocia-affected buffaloes supplemented with vitamin E and Se (78.62 +/- 2.7%, 13.38 +/- 9.75% and 28.83 +/- 7.72%, respectively) than in the unsupplemented group (54.33 +/- 12.62%, 3.48 +/- 4.16% and 17.69 +/- 12.93%, respectively). These results suggests that supplementation with antioxidants like vitamin E and Se may be beneficial in reducing oxidative stress in dystocia-affected buffaloes in the immediate postpartum period.

• Authors: A Sathya, S Prabhakar, S P S Sangha, S P S Ghuman
• Journal: Veterinary research communications (Vet Res Commun) Vol. 31 Issue 7 Pg. 809-18 (Oct 2007) ISSN: 0165-7380 [Print] Netherlands
• PMID: 17279464 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Antioxidants
• Vitamin E
• Malondialdehyde
• Glutathione Peroxidase
• Superoxide Dismutase
• Selenium
• Hydrocortisone

Topics

• Animals
• Antioxidants (administration & dosage)
• Buffaloes (physiology)
• Dietary Supplements
• Dystocia (drug therapy, veterinary)
• Female
• Glutathione Peroxidase (blood)
• Hydrocortisone (blood)
• Malondialdehyde (blood)
• Oxidative Stress (drug effects)
• Pregnancy
• Selenium (administration & dosage)
• Superoxide Dismutase (blood)
• Time Factors
• Vitamin E (administration & dosage)