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Peritoneal hemorrhage due to a ruptured ovarian cyst in ITP.

Abstract
Immune thrombocytopenic purpura in children rarely causes severe bleeding. The incidence of intracranial hemorrhage is approximately 0.2% to 1.0%, and severe bleeding (defined as persistent epistaxis, melena, menorrhagia, gastrointestinal bleeding, etc, requiring hospitalization or transfusion) occurs in only 5% of patients. Epstein-Barr virus (EBV) associated idiopathic thrombocytopenic purpura (ITP) tends to behave similarly to non-EBV - associated ITP with no increase in hemorrhagic complications and only a small increase in time to remission. Immune thrombocytopenic purpura diagnosed in adolescence is more likely to be chronic then in childhood ITP, but has a higher rate of spontaneous resolution than in adults. However, females in this age group are in their early childbearing years and present a unique set of possible hemorrhagic complications not seen in younger patients. We present the case of an 18-year-old female with EBV-associated ITP, who developed a severe intra-abdominal bleed secondary to a hemorrhagic ovarian cyst.
AuthorsJoel Kaplan, Christine C Bannon, Michael Hulse, Andrew Freiberg
JournalJournal of pediatric hematology/oncology (J Pediatr Hematol Oncol) Vol. 29 Issue 2 Pg. 117-20 (Feb 2007) ISSN: 1077-4114 [Print] United States
PMID17279009 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Immunoglobulins, Intravenous
Topics
  • Adolescent
  • Epstein-Barr Virus Infections (complications)
  • Erythrocyte Transfusion (adverse effects)
  • Female
  • Hemorrhage (etiology, therapy)
  • Humans
  • Immunoglobulins, Intravenous (therapeutic use)
  • Ovarian Cysts (complications, pathology)
  • Peritoneum (pathology)
  • Purpura, Thrombocytopenic, Idiopathic (complications)
  • Respiratory Distress Syndrome, Adult (etiology)
  • Rupture, Spontaneous (complications)
  • Tomography, X-Ray Computed

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