Peritoneal hemorrhage due to a ruptured ovarian cyst in ITP.

Immune thrombocytopenic purpura in children rarely causes severe bleeding. The incidence of intracranial hemorrhage is approximately 0.2% to 1.0%, and severe bleeding (defined as persistent epistaxis, melena, menorrhagia, gastrointestinal bleeding, etc, requiring hospitalization or transfusion) occurs in only 5% of patients. Epstein-Barr virus (EBV) associated idiopathic thrombocytopenic purpura (ITP) tends to behave similarly to non-EBV - associated ITP with no increase in hemorrhagic complications and only a small increase in time to remission. Immune thrombocytopenic purpura diagnosed in adolescence is more likely to be chronic then in childhood ITP, but has a higher rate of spontaneous resolution than in adults. However, females in this age group are in their early childbearing years and present a unique set of possible hemorrhagic complications not seen in younger patients. We present the case of an 18-year-old female with EBV-associated ITP, who developed a severe intra-abdominal bleed secondary to a hemorrhagic ovarian cyst.
AuthorsJoel Kaplan, Christine C Bannon, Michael Hulse, Andrew Freiberg
JournalJournal of pediatric hematology/oncology (J Pediatr Hematol Oncol) Vol. 29 Issue 2 Pg. 117-20 (Feb 2007) ISSN: 1077-4114 [Print] United States
PMID17279009 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Immunoglobulins, Intravenous
  • Adolescent
  • Epstein-Barr Virus Infections (complications)
  • Erythrocyte Transfusion (adverse effects)
  • Female
  • Hemorrhage (etiology, therapy)
  • Humans
  • Immunoglobulins, Intravenous (therapeutic use)
  • Ovarian Cysts (complications, pathology)
  • Peritoneum (pathology)
  • Purpura, Thrombocytopenic, Idiopathic (complications)
  • Respiratory Distress Syndrome, Adult (etiology)
  • Rupture, Spontaneous (complications)
  • Tomography, X-Ray Computed

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!

Choose Username:
Verify Password: