| Abstract | Immune thrombocytopenic purpura in children rarely causes severe bleeding. The incidence of intracranial hemorrhage is approximately 0.2% to 1.0%, and severe bleeding (defined as persistent epistaxis, melena, menorrhagia, gastrointestinal bleeding, etc, requiring hospitalization or transfusion) occurs in only 5% of patients. Epstein-Barr virus (EBV) associated idiopathic thrombocytopenic purpura (ITP) tends to behave similarly to non-EBV - associated ITP with no increase in hemorrhagic complications and only a small increase in time to remission. Immune thrombocytopenic purpura diagnosed in adolescence is more likely to be chronic then in childhood ITP, but has a higher rate of spontaneous resolution than in adults. However, females in this age group are in their early childbearing years and present a unique set of possible hemorrhagic complications not seen in younger patients. We present the case of an 18-year-old female with EBV-associated ITP, who developed a severe intra-abdominal bleed secondary to a hemorrhagic ovarian cyst. |
| Authors | Joel Kaplan, Christine C Bannon, Michael Hulse, Andrew Freiberg
(Affiliation: Pennsylvania State University, Milton S. Hershey Medical Center, PO Box 850, Hershey, PA, USA.)
|
| Journal | Journal of pediatric hematology/oncology : official journal of the American Society of Pediatric Hematology/Oncology
(J Pediatr Hematol Oncol)
Vol. 29
Issue 2
Pg. 117-20
(Feb 2007)
ISSN: 1077-4114 United States |
| PMID | 17279009
(Publication Type: Case Reports, Journal Article)
|
| Chemical References |
- Immunoglobulins, Intravenous
|
| Topics |
- Adolescent
- Epstein-Barr Virus Infections
(complications)
- Erythrocyte Transfusion
(adverse effects)
- Female
- Hemorrhage
(etiology, therapy)
- Humans
- Immunoglobulins, Intravenous
(therapeutic use)
- Ovarian Cysts
(complications, pathology)
- Peritoneum
(pathology)
- Purpura, Thrombocytopenic, Idiopathic
(complications)
- Respiratory Distress Syndrome, Adult
(etiology)
- Rupture, Spontaneous
(complications)
- Tomography, X-Ray Computed
|
