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Relief of akinetic mutism from obstructive hydrocephalus using bromocriptine and ephedrine. Case report.

AbstractThe case of a 20-year-old man with obstructive hydrocephalus who suffered multiple shunt failures and shunt revisions is presented. The patient gradually developed a clinical syndrome of akinetic mutism. This behavioral syndrome failed to respond to shunt revisions, but did improve after the administration of a combination of bromocriptine and ephedrine.
AuthorsB Anderson (Affiliation: Neurology Section, Kessler Technical Training Center Medical Center, Keesler Air Force Base, Mississippi.)
JournalJournal of neurosurgery (J Neurosurg) Vol. 76 Issue 1 Pg. 152-5 (Jan 1992) ISSN: 0022-3085 UNITED STATES
PMID1727155 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Bromocriptine
  • Ephedrine
Topics
  • Adult
  • Akinetic Mutism (drug therapy, etiology)
  • Bromocriptine (therapeutic use)
  • Cerebrospinal Fluid Shunts
  • Drug Therapy, Combination
  • Ephedrine (therapeutic use)
  • Humans
  • Hydrocephalus (complications, surgery)
  • Male