[Value of estrogen for preventing postpartum hemorrhage and shortening birth process in induce abortion].

Abstract

OBJECTIVE:

To investigate the clinical efficacy of estrogen in preventing postpartum hemorrhage and shortening the birth process during induced abortion.

METHODS:

Totally 320 puerperants for termination of pregnancy for medical reasons were randomly assigned into 2 groups, the estrogen group (n=175) and the control group (n=145), and the former were given oral estrostilben 3 mg thrice a day from the day before acrinol injection to the end of delivery. The amount of blood loss 2 h after delivery, cases of postpartum hemorrhage, and the duration of total birth process were recorded.

RESULTS:

Significant differences were noted in blood loss 2 h after delivery between estrodiol and control groups (123.3-/+81.8 vs 206.3-/+114.4 ml). Two cases of postpartum hemorrhage were found in estrogen group and 10 in control group. The duration from acrinol injection to delivery was similar between the two groups (31-/+11 vs 33-/+12 h), but the former had significant shorter duration from contraction onset to delivery than the latter (6.03-/+3.19 vs 9.7-/+5.9 h). No side-effects were found in either group.

CONCLUSION:

Estrogen given before delivery can be effective in stimulating uterine contraction for preventing postpartum hemorrhage and shortening the birth process in women undergoing induced abortion.

• Authors: Mo Zhou, Hai-Ying Wang, Chun-Yan Yang, Jing-Ling Fen
• Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University (Nan Fang Yi Ke Da Xue Xue Bao) Vol. 27 Issue 1 Pg. 92-3, 97 (Jan 2007) ISSN: 1673-4254 [Print] China
• PMID: 17259157 (Publication Type: English Abstract, Journal Article, Randomized Controlled Trial)

Chemical References

• Estrogens

Topics

• Abortion, Induced (adverse effects)
• Adult
• Estrogens (therapeutic use)
• Female
• Humans
• Labor Onset (drug effects)
• Postpartum Hemorrhage (etiology, prevention & control)
• Pregnancy
• Time Factors
• Treatment Outcome
• Uterine Contraction (drug effects)