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Resolution of a phytobezoar with Aldoph's Meat Tenderizer.

Abstract
A 58-year-old man went to his physician with complaints of midepigastric pain, flatulence, belching, and shortness of breath. During a physical examination, the patient was in no acute distress. The patient underwent an ultrasound examination, which revealed cholelithiasis, a laparoscopic cholecystectomy, which revealed chronic gallbladder disease, and esophagogastroduodenoscopy, which revealed gastritis, a hiatal hernia, and a phytobezoar. To treat the bezoar, the patient was given Adolph's Meat Tenderizer 1 teaspoonful in 8 oz of water before each meal for 7 days. This product contains papain, a proteolytic enzyme, that is thought to cleave protein linkages within bezoars. The patient's symptoms resolved with no adverse events reported, and follow-up endoscopy revealed resolution of the phytobezoar. Although a few other agents are used to treat phytobezoars, little clinical data exist on their safety and effectiveness. Adolph's Meat Tenderizer appears to be a safe and effective treatment for patients with a phytobezoar.
AuthorsErica L Baker, William L Baker, David J Cloney
JournalPharmacotherapy (Pharmacotherapy) Vol. 27 Issue 2 Pg. 299-302 (Feb 2007) ISSN: 0277-0008 [Print] United States
PMID17253920 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Drug Combinations
  • Sodium, Dietary
  • meat tenderizer
  • Papain
Topics
  • Bezoars (diagnosis, drug therapy)
  • Drug Combinations
  • Humans
  • Male
  • Middle Aged
  • Papain (therapeutic use)
  • Sodium, Dietary (therapeutic use)
  • Treatment Outcome

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