Post-traumatic spontaneous recurrent hypothermia: a variant of Shapiro's syndrome.

Abstract

A 49-year-old man presented with episodic hypothermia many years after sustaining a contusional brain injury. Brain magnetic resonance imaging demonstrated the destruction of the anterior parts of the corpus callosum without hypothalamic lesions. Nevertheless, delayed hypothalamic dysfunction at the neurotransmitter level is the probable pathophysiological key factor. Clomipramine treatment was beneficial. This case expands the spectrum of Shapiro's syndrome.

• Authors: D M Hemelsoet, J L De Bleecker
• Journal: European journal of neurology (Eur J Neurol) Vol. 14 Issue 2 Pg. 224-7 (Feb 2007) ISSN: 1468-1331 [Electronic] England
• PMID: 17250734 (Publication Type: Case Reports, Journal Article)

Chemical References

• Clomipramine

Topics

• Body Temperature (drug effects)
• Brain Injuries (complications, diagnosis)
• Clomipramine (therapeutic use)
• Corpus Callosum (pathology)
• Humans
• Hypothermia (drug therapy, etiology, physiopathology)
• Magnetic Resonance Imaging
• Male
• Middle Aged
• Syndrome