First experiences with the collagen-elastin matrix Matriderm as a dermal substitute in severe burn injuries of the hand.

Abstract

Restoring function after hand burns plays a major role in the restitution of a quality of life. Thereby the reconstructed pliability of the grafted areas is of utmost importance for good hand function. The collagen elastin matrix Matriderm was evaluated as a dermal substitute for the treatment of severe hand burns. In a series of 10 patients, mean age 43 years, TBSA 22.8%, an early debridement and immediate grafting with the matrix and unmeshed skin graft was carried out in a one-stage procedure. In the early postoperative follow up an overall take rate of 97% was observed. In contrast to conventional skin grafts, the color of the skin grafts over the matrix appeared pale in the first few days, but after 2 weeks no difference was observed. After three months, pliability of the grafted area was excellent, (mean VSS 3.2+/-1.2). Full range of motion was achieved in all hands, no blisters and no unstable or hypertrophic scars occurred. Matriderm has proved to be a dermal substitute suitable for the treatment of hand burns. We therefore consider Matriderm as a promising dermal substitute for the treatment of severe hand burns.

• Authors: W Haslik, L-P Kamolz, G Nathschläger, H Andel, G Meissl, M Frey
• Journal: Burns : journal of the International Society for Burn Injuries (Burns) Vol. 33 Issue 3 Pg. 364-8 (May 2007) ISSN: 0305-4179 [Print] Netherlands
• PMID: 17240532 (Publication Type: Journal Article)

Chemical References

• Collagen
• Elastin

Topics

• Adult
• Burns (therapy)
• Collagen (therapeutic use)
• Elastin (therapeutic use)
• Female
• Graft Survival
• Hand Injuries (therapy)
• Humans
• Male
• Middle Aged
• Skin, Artificial
• Treatment Outcome