[A long term survival case of advanced intrahepatic cholangiocarcinoma treated with multidisciplinary treatment].
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| Abstract |
A 56-year-old man was admitted to our hospital for liver tumor of 7 cm in diameter, located mainly in the anterior segment. He underwent a hepatic resection of anterior and median segment of the liver in January 2002. Pathologically, the tumor was moderately differentiated intrahepatic cholangiocarcinoma (ICC) with vascular invasion. Hepatic arterial chemotherapy as a neoadjuvant therapy was performed. In December 2002, bone metastases in the 12th thoracic spine and iliac bone were found. Therefore, he received radiotherapy (total of 30 Gy) and a monthly bisphosphonate infusion. In May 2003, multiple intrahepatic recurrences were diagnosed. Transarterial chemoembolization for twice and an additional radio-frequency ablation were performed. Four months later, lung metastases were found, thus, he was administered TS-1. He has been alive with PS 0 for 4 and half years after the hepatic resection. No new intrahepatic recurrences were found and bone and lung metastases remained to be stable. Although only a hepatic resection is a useful therapy for ICC, such a multidisciplinary treatment may have an effect to improve the prognosis of patients with ICC.
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| Authors | Toshiro Masuda, Toru Beppu, Takatoshi Ishiko, Takao Mizumoto, Seiji Hosaka, Osamu Nakahara, Hiromitsu Hayashi, Hirohisa Okabe, Tsuyoshi Yamanaka, Kazutoshi Okabe, Hiroshi Takamori, Keiichiro Kanemitsu, Masahiko Hirota, Hideo Baba |
| Journal | Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 33 Issue 12 Pg. 1944-6 (Nov 2006) ISSN: 0385-0684 [Print] Japan |
| PMID | 17212154 (Publication Type: Case Reports, English Abstract, Journal Article) |
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