Enantioselective intramolecular aldol addition/dehydration reaction of a macrocyclic diketone: synthesis of the musk odorants (R)-muscone and (R,Z)-5-muscenone.

• Authors: Oliver Knopff, Jérôme Kuhne, Charles Fehr
• Journal: Angewandte Chemie (International ed. in English) (Angew Chem Int Ed Engl) Vol. 46 Issue 8 Pg. 1307-10 ( 2007) ISSN: 1433-7851 [Print] Germany
• PMID: 17211908 (Publication Type: Journal Article)

Chemical References

• (R,Z)-5-muscenone
• Aldehydes
• Cycloparaffins
• Ketones
• Macrocyclic Compounds
• Water
• 3-hydroxybutanal
• muscone

Topics

• Aldehydes (chemistry)
• Cycloparaffins (chemical synthesis, chemistry)
• Ketones (chemical synthesis, chemistry)
• Kinetics
• Macrocyclic Compounds (chemical synthesis, chemistry)
• Models, Molecular
• Molecular Structure
• Stereoisomerism
• Water (chemistry)