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Talampanel.

Abstract
Talampanel is a novel anticonvulsant that acts as an allosteric inhibitor of the AMPA receptor. Talampanel has a broad spectrum of action in animal models of epilepsy and neuroprotection. Clinical experience to date has been able to show effectiveness in reduction of seizures in patients with refractory partial seizures.
AuthorsJohn F Howes, Cynthia Bell
JournalNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics (Neurotherapeutics) Vol. 4 Issue 1 Pg. 126-9 (Jan 2007) ISSN: 1933-7213 [Print] United States
PMID17199027 (Publication Type: Journal Article, Review)
Chemical References
  • Antineoplastic Agents
  • Benzodiazepines
  • talampanel
Topics
  • Animals
  • Antineoplastic Agents
  • Benzodiazepines
  • Brain (drug effects)
  • Clinical Trials as Topic
  • Epilepsy (drug therapy)
  • Humans

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