| Abstract | We report a recurrent case of gastric endocrine cell cancer that showed a remarkable response to systemic chemotherapy. A 70-year-old male who underwent gastroscopy at our hospital showed a 0-IIa-like lesion, but no abnormal CT findings. He was diagnosed with gastric cancer, and underwent a proximal gastrectomy. The resected specimen showed endocrine cell cancer. The tumor was Grimelius-positive histologically and chromogranin A-and NSE-positive immunohistochemically. About 2 years after surgery, liver, lymph node, and bone metastases were detected. Systemic chemotherapy with TS-1 and CDDP was started, and the lesions progressed. Then, by approximately 1 year after CDDP and CPT-11 treatments, the recurrent lesions had diminished remarkably and were no longer seen on CT or FDG-PET. |
| Authors | Yutaka Sunose, Izumi Takeyoshi, Susumu Kawate, Kunihiro Hamada, Hirofumi Tsutsumi, Kazuhisa Arakawa, Nozomi Tohgo, Hiroyuki Toya, Susumu Ohwada, Kenji Kashiwabara, Yasuo Morishita
(Affiliation: Dept. of Thoracic and Visceral Organ Surgery, Gunma University School of Medicine.)
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| Journal | Gan to kagaku ryoho. Cancer & chemotherapy
(Gan To Kagaku Ryoho)
Vol. 33
Issue 13
Pg. 2073-6
(Dec 2006)
ISSN: 0385-0684 Japan |
| PMID | 17197757
(Publication Type: Case Reports, English Abstract, Journal Article)
|
| Chemical References |
- irinotecan
- Cisplatin
- Camptothecin
|
| Topics |
- Adenocarcinoma
(drug therapy, pathology, secondary, surgery)
- Aged
- Antineoplastic Combined Chemotherapy Protocols
(therapeutic use)
- Bone Neoplasms
(drug therapy, secondary)
- Camptothecin
(administration & dosage, analogs & derivatives)
- Carcinoma, Small Cell
(drug therapy, pathology, secondary, surgery)
- Cisplatin
(administration & dosage)
- Drug Administration Schedule
- Gastrectomy
- Humans
- Liver Neoplasms
(drug therapy, secondary)
- Male
- Remission Induction
- Stomach Neoplasms
(drug therapy, pathology, surgery)
|
