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Nursing considerations for clofarabine in the treatment of acute lymphoblastic leukemia in children.

AbstractEach year, almost 3500 children are diagnosed with leukemia, representing approximately 30% of pediatric cancer cases. Acute lymphoblastic leukemia is the most common form of pediatric leukemia, accounting for approximately 80% of cases. A significant number of children fail to respond to existing chemotherapies or are unable to maintain remission. Their prognosis is poor, with little hope for long-term survival.
AuthorsLisa R McDonald, Colleen H McCarthy (Affiliation: University of Texas M.D. Anderson Cancer Center, Houston, USA. lrmcdona at mdanderson.org)
JournalClinical journal of oncology nursing (Clin J Oncol Nurs) Vol. 10 Issue 6 Pg. 809-15 (Dec 2006) ISSN: 1092-1095 United States
PMID17193947 (Publication Type: Journal Article, Review)
Chemical References
  • Adenine Nucleotides
  • Arabinonucleosides
  • clofarabine
Topics
  • Adenine Nucleotides (adverse effects, therapeutic use)
  • Arabinonucleosides (adverse effects, therapeutic use)
  • Child
  • Clinical Trials, Phase II as Topic
  • Drug Administration Schedule
  • Drug Monitoring
  • Humans
  • Nurse's Role
  • Oncologic Nursing (organization & administration)
  • Practice Guidelines as Topic
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma (drug therapy, epidemiology, nursing)
  • Prognosis
  • Recurrence
  • Remission Induction
  • Survival Rate
  • Treatment Outcome