Combined chemotherapy and radiotherapy for advanced maxillary ameloblastoma. A case report.

Abstract

A case of advanced maxillary ameloblastoma was successfully treated with combined intra-arterial chemotherapy (Peplomycin, 85 mg) and radiotherapy (Co60, 7080 r). The tumour showed a remarkable shrinkage, and the patient survived. He is still alive and well at the time of this report. Carefully applied chemotherapy combined with radiotherapy has a useful role in the management of ameloblastoma especially in an advanced maxillary tumour. This report presents a typical example, which indicates that the ameloblastoma may not be an inherently radioresistant and chemoresistant tumour.

• Authors: M Ueda, T Kaneda
• Journal: Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery (J Craniomaxillofac Surg) Vol. 19 Issue 6 Pg. 272-4 (Aug 1991) ISSN: 1010-5182 [Print] Scotland
• PMID: 1719032 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antibiotics, Antineoplastic
• Cobalt Radioisotopes
• Bleomycin
• Peplomycin

Topics

• Ameloblastoma (drug therapy, radiotherapy)
• Antibiotics, Antineoplastic (administration & dosage, therapeutic use)
• Bleomycin (administration & dosage, therapeutic use)
• Cobalt Radioisotopes (therapeutic use)
• Combined Modality Therapy
• Humans
• Injections, Intra-Arterial
• Male
• Maxillary Neoplasms (drug therapy, radiotherapy)
• Middle Aged
• Neoplasms, Second Primary (drug therapy, radiotherapy)
• Peplomycin