| Abstract | PURPOSE: To determine visual outcome after a 12-month follow-up period of verteporfin therapy for subfoveal choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD) in Indian patients. METHODS: Twenty-five patients (26 eyes) who completed a 12-month follow-up after photodynamic therapy for subfoveal CNV secondary to AMD were included in the study. The follow-up schedule was every month for 2 months and then every 3 months thereafter until 12 months. Improvement in visual acuity was defined as a >or=10-letter gain, and deterioration as a >or=10-letter loss in the Early Treatment Diabetic Retinopathy Study chart at 4 m. RESULTS: The mean age of the 25 patients was 62.3 +/- 9 years. There were 17 male patients (68%). The mean initial letter acuity was 28. 4 +/- 14.1, and the final letter acuity was 25.5 +/- 18.4 at 12 months. Initial visual acuity was >or=20/40 in seven eyes, 20/50-20/80 in nine eyes, and 20/100-20/200 in ten eyes; seven eyes had a >or=10-letter gain, and three eyes had a >or=10-letter loss. At the end of 12 months, six eyes had a >or=10-letter gain and ten eyes had a >or=10-letter loss. CONCLUSION: Photodynamic therapy appears to preserve the vision in subfoveal CNV secondary to AMD in the eyes of Indian patients. |
| Authors | Nazimul Hussain, Taraprasad Das, Rohit Khanna, Kallukuri Sumasri, Lakshmana Samudram Mohan Ram
(Affiliation: Smt. Kanuri Santhamma Retina Vitreous Centre, Hyderabad, Andhra Pradesh, India. nazimul at lvpei.org)
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| Journal | Japanese journal of ophthalmology
(Jpn J Ophthalmol)
2006 Nov-Dec
Vol. 50
Issue 6
Pg. 524-8
ISSN: 0021-5155 Japan |
| PMID | 17180526
(Publication Type: Journal Article)
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| Chemical References |
- Photosensitizing Agents
- Porphyrins
- verteporfin
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| Topics |
- Aged
- Choroidal Neovascularization
(drug therapy, etiology)
- Female
- Humans
- India
- Macular Degeneration
(complications, drug therapy)
- Male
- Middle Aged
- Photochemotherapy
- Photosensitizing Agents
(therapeutic use)
- Porphyrins
(therapeutic use)
- Prospective Studies
- Visual Acuity
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