[Usage of the new parenteral selective cox-2 inhibitor dynastat in the gynecologic practice].

Abstract

A follow-up of 180 women was carried out. The patients having endured different gynecological operations (laparoscopy, laparohysterectomy, etc.) were divided into two main groups: half of them were treated with Dynastat (new selective COX-2 inhibitor) and the others were treated with Profenid (conventional nonsteroidal anti-inflammatory drug). The groups were compared by the quality of the achieved analgesia and appeared side effects, especially postoperative nausea and vomiting. These parameters were assessed by both medics and patients. In conclusion we accept that the new COX-2 selective inhibitor Dynastat does not have advantages over traditional nonsteroidal anti-inflammatory drug as Profenid especially for postoperative nausea and vomiting and quality of analgesia.

• Authors: B Tablov, V Tablov, I Popov, S Stoĭkov
• Journal: Akusherstvo i ginekologiia (Akush Ginekol (Sofiia)) Vol. 45 Issue 5 Pg. 10-3 ( 2006) ISSN: 0324-0959 [Print] Bulgaria
• PMID: 17168490 (Publication Type: English Abstract, Journal Article, Randomized Controlled Trial)

Chemical References

• Cyclooxygenase 2 Inhibitors
• Isoxazoles
• parecoxib

Topics

• Adolescent
• Adult
• Aged
• Cyclooxygenase 2 Inhibitors (administration & dosage, therapeutic use)
• Female
• Gynecologic Surgical Procedures (methods)
• Humans
• Infusions, Intravenous
• Isoxazoles (administration & dosage, therapeutic use)
• Middle Aged
• Pain Measurement
• Pain, Postoperative (drug therapy)
• Prospective Studies