[A case of rheumatoid lung complicated by SELAPINA-induced pneumonia].

Abstract

SELAPINA is generic product of PL granule which is one of the most common forms of combination remedies for the common cold in Japan, and includes acetaminophen. We report a case of SELAPINA-induced pneumonia successfully treated with glucocorticoid pulse therapy followed by orally administered prednisolone. A 68-year-old woman, who had been treated for rheumatoid arthiritis with pulmonary involvement, took SELAPINA with an antibiotic for 6 days because of her cold symptoms. She then suffered a high fever, cough, dyspnea, vomiting and diarrhea. Chest radiograph and high-resolution computed tomography (HRCT) scan revealed diffuse interstitial shadows. SELAPINA-induced pneumonia was diagnosed because the blastoid transformation test using her peripheral blood lymphocytes was positive on stimulation with SELAPINA, but negative for other medicines.

• Authors: Seiko Nakayama, Hiroshi Mukae, Yuji Ishimatsu, Kanako Sugiyama, Mioko Ide, Hiroshi Ishimoto, Keiko Hisatomi, Hiroshi Ishii, Koh Abel, Yoshiyuki Ozono, Shigeru Kohno
• Journal: Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society (Nihon Kokyuki Gakkai Zasshi) Vol. 44 Issue 11 Pg. 858-63 (Nov 2006) ISSN: 1343-3490 [Print] Japan
• PMID: 17144587 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Drug Combinations
• SELAPINA
• Acetaminophen
• Amiodarone

Topics

• Acetaminophen (adverse effects)
• Aged
• Amiodarone (adverse effects)
• Arthritis, Rheumatoid (complications, drug therapy)
• Drug Combinations
• Female
• Humans
• Lung Diseases (complications)
• Pneumonia (chemically induced)
• Rheumatic Diseases (complications)