[A case of malignant mesothelioma presenting with recurrent pneumothorax].

Abstract

A 71-year-old man was found to have right hydropneumothorax by chest X-ray film on a regular checkup. Thoracic drainage and bullectomy by thoracoscopy did not improve the pneumothorax, so pleurodesis with OK-432 was done. Pneumothorax recurred twice, requiring thoracic drainage and pleurodesis. Although pneumothorax was treated successfully, increased pleural effusion, pleural thickening and subcutaneal tumor at the thoracic drainage suture site developed. The concentration of hyaluronic acid in the pleural fluid was very high. The histological examination of the biopsied subcutaneous tumor showed mixed type malignant pleural mesothelioma. Chemotherapy with gemcitabine and vinorelbine could not control the progression.

• Authors: Nobuyuki Katayam, Akira Tokuda, Yasuto Nakatsumi, Yoshitaka Oribe, Masaki Fujimura
• Journal: Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society (Nihon Kokyuki Gakkai Zasshi) Vol. 44 Issue 11 Pg. 807-11 (Nov 2006) ISSN: 1343-3490 [Print] Japan
• PMID: 17144577 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antineoplastic Agents
• Picibanil

Topics

• Aged
• Antineoplastic Agents (therapeutic use)
• Disease Progression
• Fatal Outcome
• Humans
• Male
• Mesothelioma (diagnosis, pathology)
• Picibanil (therapeutic use)
• Pleural Neoplasms (diagnosis, pathology)
• Pneumothorax (diagnostic imaging, etiology, therapy)
• Radiography
• Recurrence