The effect of zaltoprofen on physiotherapy for limited shoulder movement in breast cancer patients: a single-blinded before-after trial.

Abstract

OBJECTIVE:

To determine the efficacy of oral administration of zaltoprofen on shoulder range of motion (ROM) exercises for breast cancer patients after surgery.

DESIGN:

Single-blind, before-after trial.

SETTING:

Rehabilitation facility in a Japanese university hospital.

PARTICIPANTS:

Forty breast cancer patients (age range, 37-72y) with limited shoulder movement after surgery.

INTERVENTION:

Single session of physiotherapy (PT) with or without oral administration of zaltoprofen.

MAIN OUTCOME MEASURES:

Active shoulder ROM in flexion, abduction, and external rotation, as well as subjective pain score during shoulder movements.

RESULTS:

Active shoulder movements after ingesting a zaltoprofen tablet significantly improved in flexion, abduction (P<.001), and external rotation (P<.005). PT treatment improved flexion and abduction ROM in both the zaltoprofen and control groups and led to significantly larger flexion and abduction movements in the zaltoprofen group than in the control group (P<.01). There were no differences in pain scores between groups, but 2 patients who did not receive zaltoprofen complained of increased pain just after ROM exercises.

CONCLUSION:

Zaltoprofen taken orally before ROM exercises for painful shoulder after breast cancer surgery may enhance the effects of PT.

• Authors: Kimitaka Hase, Michiyo Kamisako, Toshiyuki Fujiwara, Tetsuya Tsuji, Meigen Liu
• Journal: Archives of physical medicine and rehabilitation (Arch Phys Med Rehabil) Vol. 87 Issue 12 Pg. 1618-22 (Dec 2006) ISSN: 0003-9993 [Print] United States
• PMID: 17141642 (Publication Type: Journal Article, Randomized Controlled Trial)

Chemical References

• Anti-Inflammatory Agents, Non-Steroidal
• Benzopyrans
• Propionates
• pyranoprofen

Topics

• Adult
• Aged
• Anti-Inflammatory Agents, Non-Steroidal (therapeutic use)
• Benzopyrans (therapeutic use)
• Breast Neoplasms (physiopathology, surgery)
• Female
• Humans
• Middle Aged
• Movement (physiology)
• Pain Measurement
• Physical Therapy Modalities
• Postoperative Complications (physiopathology)
• Propionates (therapeutic use)
• Range of Motion, Articular (physiology)
• Shoulder Joint (physiopathology)
• Shoulder Pain (drug therapy, physiopathology)
• Single-Blind Method