[Role of 18Fluorine-deoxyglucose (FDG) positron emission tomography in the management of lymphomas].

Abstract

Positron emission tomography (PET) with fluorine-18 labeled deoxyglucose (FDG) is useful in the management of lymphomas. In this review, some general concepts of this metabolic test are defined. It has an excellent diagnostic yield in Hodgkin disease as well as in most non Hodgkin lymphomas. Staging, restaging residual mass evaluation and the control of therapy are the main indications for FDG-PET. Images with FDG have a high diagnostic and prognostic value, that is superior to anatomical images and conventional staging techniques. They are also helpful for the assessment of tumor activity in abnormal lymph nodes or large masses that have been treated and reduce their size slowly or show an incomplete resolution. Currently, the resolution of dedicated PET equipments is 6 mm and bigger lesions can easily be detected. The main differences and advantages of FDG versus gallium-67 in lymphoma are also discussed, as well as the initial local experience with the technique in lymphoma patients.

• Authors: Teresa Massardo V, José Canessa G, M Josefina Jofré M, Patricio González E, Pamela Humeres A, Paulina Sierralta G
• Journal: Revista medica de Chile (Rev Med Chil) Vol. 134 Issue 7 Pg. 910-9 (Jul 2006) ISSN: 0034-9887 [Print] Chile
• Vernacular Title: Utilidad de la deoxiglucosa marcada con flúor-18 (FDG) en el manejo de los linfomas.
• PMID: 17130976 (Publication Type: Journal Article, Review)

Chemical References

• Gallium Radioisotopes
• Radiopharmaceuticals
• Fluorodeoxyglucose F18

Topics

• Adult
• Aged
• Aged, 80 and over
• Disease-Free Survival
• Female
• Fluorodeoxyglucose F18
• Gallium Radioisotopes
• Hodgkin Disease (diagnostic imaging, pathology, radiotherapy)
• Humans
• Lymphoma, Non-Hodgkin (diagnostic imaging, pathology, radiotherapy)
• Male
• Neoplasm Staging
• Positron-Emission Tomography
• Prognosis
• Radiopharmaceuticals
• Sensitivity and Specificity