Abstract | OBJECTIVE: To investigate whether the effect of Biminne on allergic rhinitis (AR) was through improving vascular permeability of nasal mucosa. METHODS: RESULTS: EBD concentration was higher in the model rats than that in the normal rats, and lower in the Biminne-treated rats than that in the model rats (both P < 0.01). CONCLUSION:
Biminne could improve vascular permeability of nasal mucosa in sensitized rats, which may be the mechanism of its clinical effect on AR.
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Authors | Yi-feng Gu, Xin-min Zhang, Guo-rang Hu |
Journal | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine
(Zhongguo Zhong Xi Yi Jie He Za Zhi)
Vol. 26
Issue 10
Pg. 918-21
(Oct 2006)
ISSN: 1003-5370 [Print] China |
PMID | 17121045
(Publication Type: English Abstract, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Anti-Allergic Agents
- Drugs, Chinese Herbal
- biminne
- Ovalbumin
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Topics |
- Animals
- Anti-Allergic Agents
(pharmacology)
- Capillary Permeability
(drug effects)
- Drugs, Chinese Herbal
(pharmacology)
- Injections, Intraperitoneal
- Male
- Nasal Mucosa
(blood supply)
- Ovalbumin
(administration & dosage, toxicity)
- Rats
- Rats, Inbred BN
- Rhinitis, Allergic, Perennial
(chemically induced, physiopathology)
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