Abstract | INTRODUCTION: MATERIALS AND METHODS: RESULTS: The mean graft survival was 87.4 +/- 46.8 months. The graft survival rates in FSGS recipients were at 1 year, 100%; 5 years, 79.6%; 10 years, 68.2%. Two out of four recipients experienced graft loss due to chronic rejection. The other two out of four recipients with graft loss displayed severe proteinuria diagnosed as recurrence of FSGS. To treat recurrent FSGS, plasma exchange was partially effective to reduce proteinuria. CONCLUSION: Our incidence of recurrent FSGS is 16.7% with graft survivals at 5 and 10 years of 79.6% and 68.2%, respectively. The recurrence of FSGS happened after scheduled reductions in immunosuppressants. Careful observation is required with maintenance of immunosuppression in these patients.
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Authors | K Akioka, M Okamoto, Y Wakabayashi, S Nobori, S Ogino, H Ushigome, K Uryuhara, S Kaihara, N Yoshimura |
Journal | Transplantation proceedings
(Transplant Proc)
Vol. 38
Issue 9
Pg. 2819-22
(Nov 2006)
ISSN: 0041-1345 [Print] United States |
PMID | 17112838
(Publication Type: Journal Article)
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Topics |
- Biopsy
- Family
- Female
- Follow-Up Studies
- Glomerulosclerosis, Focal Segmental
(pathology, surgery)
- Graft Survival
- Humans
- Kidney Transplantation
(physiology)
- Living Donors
- Male
- Transplantation, Homologous
- Treatment Outcome
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