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Artificial nutrition and hydration in terminal cancer patients: the real and the ideal.

AbstractINTRODUCTION: To better understand current practice relating to artificial nutrition/hydration in terminal cancer patients, we enrolled terminal cancer patients who were admitted at Seoul National University Boramae Hospital for supportive care only and who died with a duration of hospital stay to death of more than 1 week between 2003 and 2004. We detailed oral intake and intravenous nutrition/hydration status on admission, 1 week after admission, and 2 days before death. Administered calories and changes in these according to time and "DNR" (do-not-resuscitate) status were noted. RESULTS: Of the total 165 patients, oral intake was possible in 84 patients (50.9%) on admission, in 79 patients (47.8%) on 1 week after admission, and in 29 patients (17.5%) 2 days before death (p < 0.01). Intravenous nutrition/hydration was administered to 133 patients (80.6%) on admission, to 125 patients (75.7%) at 1 week, and to 137 patients (83.0%) 2 days before death (p = 0.7). The calories administered to the patient by oral intake were 393 kcal on admission, 353 kcal 1 week after admission, and 89 kcal 2 days before death. In addition, the calories delivered by intravenous fluid were 369, 386 and 465 kcal, respectively. Near to death, calories by oral intake continuously reduced (p < 0.01) and intravenous calories continuously increased (p = 0.04), but total administered calories reduced (p = 0.03). Intravenous nutrition/hydration stopped after the attainment of the advance directive of DNR in 9% of patients. CONCLUSION: This study showed the high prevalence of artificial nutrition/hydration, especially intravenous infusion, in Korean terminal cancer patients compared with situation in other countries. More studies are needed to verify the efficacy of artificial nutrition/hydration in terminal cancer patients.
AuthorsDo Youn Oh, Jee Hyun Kim, Se Hoon Lee, Dong Wan Kim, Seock Ah Im, Tae You Kim, Dae Seog Heo, Yung Jue Bang, Noe Kyeong Kim (Affiliation: Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, 28 Yongon-Dong, Chongno-Gu, Seoul, South Korea. ohdoyoun at snu.ac.kr)
JournalSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer (Support Care Cancer) Vol. 15 Issue 6 Pg. 631-6 (Jun 2007) ISSN: 0941-4355 Germany
PMID17102940 (Publication Type: Journal Article)
Topics
  • Adult
  • Aged
  • Feeding Behavior
  • Female
  • Fluid Therapy (methods, statistics & numerical data)
  • Humans
  • Korea
  • Length of Stay (statistics & numerical data)
  • Male
  • Middle Aged
  • Neoplasms (therapy)
  • Nutritional Support (methods, statistics & numerical data)
  • Patient Acceptance of Health Care (statistics & numerical data)
  • Patient Compliance
  • Resuscitation Orders
  • Terminal Care (methods, statistics & numerical data)
  • Terminally Ill