Transfusion support to Dengue patients in a hospital based blood transfusion service in north India.

Abstract

We evaluated transfusion requirements in a retrospective study of 245 patients with various categories of Dengue infection. The majority (155/245) of our patients were of the Dengue fever (DF) category. There was no correlation between clinical bleed and platelet count as 81 non-bleeding patients were having counts < 20 x 10(3)/microL. Coagulopathy was observed in 37% of the patients with Dengue hemorrhagic fever or Dengue shock syndrome. A rapid response to platelet and fresh frozen plasma (FFP) transfusion was observed in all cases. However, inappropriate transfusion was a major concern as transfusion of 21.5% platelet concentrates was considered inappropriate.

• Authors: Rajendra Chaudhary, Dheeraj Khetan, Seema Sinha, Pratul Sinha, Atul Sonker, Prashant Pandey, Sudipta Sekhar Das, Prashant Agarwal, Vijaylaxmi Ray
• Journal: Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis (Transfus Apher Sci) Vol. 35 Issue 3 Pg. 239-44 (Dec 2006) ISSN: 1473-0502 [Print] England
• PMID: 17097349 (Publication Type: Journal Article)

Topics

• Adolescent
• Adult
• Aged
• Blood Coagulation Disorders (diagnosis, etiology, therapy)
• Blood Transfusion (standards, statistics & numerical data)
• Child
• Child, Preschool
• Female
• Humans
• India
• Infant
• Inpatients (statistics & numerical data)
• Male
• Middle Aged
• Platelet Count
• Platelet Transfusion (standards, statistics & numerical data)
• Retrospective Studies
• Severe Dengue (blood, complications, therapy)
• Utilization Review