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Could ATRA/Idarubicin treatment of acute promyelocytic leukemia induce the appearance of new clonal cytogenetic abnormalities in patients in complete remission?

AuthorsMar Mallo, Marta Salido, Blanca Espinet, José Cervera, Anna Canellas, Juan Carlos Pajuelo, Carmen Pedro, Lourdes Florensa, Miguel Angel Sanz, Francesc Solé
JournalLeukemia research (Leuk Res) Vol. 31 Issue 9 Pg. 1315-7 (Sep 2007) ISSN: 0145-2126 [Print] England
PMID17092559 (Publication Type: Letter, Research Support, Non-U.S. Gov't)
Chemical References
  • DNA, Neoplasm
  • Tretinoin
  • Idarubicin
Topics
  • Adolescent
  • Adult
  • Aged
  • Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
  • Child
  • Chromosome Aberrations (drug effects)
  • Chromosomes, Human, Pair 20 (genetics)
  • DNA, Neoplasm (genetics)
  • Female
  • Humans
  • Idarubicin (administration & dosage)
  • Leukemia, Promyelocytic, Acute (drug therapy, genetics, pathology)
  • Male
  • Middle Aged
  • Remission Induction
  • Survival Rate
  • Translocation, Genetic
  • Tretinoin (administration & dosage)

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