SearchDictionaryMobileLogin

Smoking-responsive juvenile-onset Parkinsonism.

AbstractWe describe a patient with juvenile levodopa-responsive Parkinsonism who reported a dramatic response to cigarette smoking with transient but marked improvement of motor symptoms associated with oculogyric crises and psychotic behavior. His beta-CIT single-photon emission computed tomography scan showed a complete absence of presynaptic dopaminergic nerve terminals.
AuthorsHasmet Ayhan Hanagasi, Andrew Lees, Janel O Johnson, Andrew Singleton, Murat Emre (Affiliation: Department of Neurology, Behavioral Neurology and Movement Disorders Unit, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey. hasmet at yahoo.com)
JournalMovement disorders : official journal of the Movement Disorder Society (Mov Disord) Vol. 22 Issue 1 Pg. 115-9 (Jan 2007) ISSN: 0885-3185 United States
PMID17080433 (Publication Type: Case Reports, Journal Article)
CopyrightCopyright 2006 Movement Disorder Society.
Chemical References
  • Nicotinic Agonists
  • Tropanes
  • 2-carbomethoxy-8-(3-fluoropropyl)-3-(4-iodophenyl)tropane
  • Nicotine
Topics
  • Adult
  • Humans
  • Male
  • Nicotine (therapeutic use)
  • Nicotinic Agonists (therapeutic use)
  • Parkinsonian Disorders (drug therapy, radionuclide imaging)
  • Smoking
  • Tomography, Emission-Computed, Single-Photon
  • Tropanes (pharmacokinetics)