Abstract |
We report a leukemic patient with C. krusei fungemia who failed to respond to liposomal amphotericin B therapy alone. The addition of caspofungin eradicated infection and was well tolerated. Our report is the first to describe successful treatment of a patient with invasive C. krusei infection using this combination of antifungals. Combination therapy could be a useful treatment option for invasive candidosis, particularly when caused by more resistant species such as C. krusei.
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Authors | W J Olver, F Scott, G S Shankland |
Journal | Medical mycology
(Med Mycol)
Vol. 44
Issue 7
Pg. 655-7
(Nov 2006)
ISSN: 1369-3786 [Print] England |
PMID | 17071561
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Echinocandins
- Lipopeptides
- Peptides, Cyclic
- Amphotericin B
- Caspofungin
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Topics |
- Adult
- Amphotericin B
(pharmacology, therapeutic use)
- Candida
(drug effects, isolation & purification)
- Candidiasis
(drug therapy, microbiology)
- Caspofungin
- Drug Therapy, Combination
- Echinocandins
- Fungemia
(drug therapy)
- Humans
- Leukemia
(complications, drug therapy)
- Lipopeptides
- Male
- Peptides, Cyclic
(pharmacology, therapeutic use)
- Treatment Outcome
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