Abstract |
We describe a patient with Ross syndrome who had the classic triad of segmental anhidrosis, tonic pupils and hyporeflexia. Dilute pilocarpine (0.1%) instillation in both eyes revealed parasympathetic denervation hypersensitivity. There was evidence of cardiac dysautonomia in the form of a decrease in heart rate variability with deep breathing and an abnormal Valsalva response. A thermoregulatory sweat test showed the presence of sweating in the right cheek, neck and upper one-third of the left arm and shoulder only. Sympathetic skin responses were absent in the affected segments of the upper limb. Ross syndrome is a degenerative disorder that progressively involves different fibre populations, starting with autonomic fibres and then involving the unmyelinated and myelinated sensory fibres. A careful clinical examination and simple bedside autonomic tests can confirm the diagnosis.
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Authors | Thomas Chemmanam, Jeyaraj D Pandian, Randhir S Kadyan, S M Bhatti |
Journal | Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
(J Clin Neurosci)
Vol. 14
Issue 1
Pg. 94-6
(Jan 2007)
ISSN: 0967-5868 [Print] Scotland |
PMID | 17070054
(Publication Type: Case Reports, Journal Article)
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Chemical References |
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Topics |
- Adult
- Autonomic Nervous System Diseases
(complications, diagnosis)
- Blood Pressure
(drug effects)
- Humans
- Hypohidrosis
(diagnosis, etiology)
- Male
- Miotics
- Neural Conduction
- Pilocarpine
- Pupil
(physiology)
- Reflex, Abnormal
(physiology)
- Syndrome
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