[Use of partially covered nitinol stents in malignant gastroduodenal obstructions].

Abstract

OBJECTIVE:

To demonstrate our experience with self-expanding nitinol duodenal stents in the treatment of inoperable malignant gastroduodenal obstructions.

MATERIALS AND METHODS:

Seventy two (72) patients with malignant gastroduodenal obstruction, 42 men and 30 women, were treated with peroral application of a gastroduodenal nitinol stent. The average age was 61.3 years (range of 21 to 92 years). The gastroduodenal obstructions was caused by gastric tumors (38 patients), pancreatic tumors (15), gallbladder tumors (8), bile duct tumors (5), metastatic tumors (4) and two cases of duodenal invasion by regional tumor (colon and hypernephroma). These conditions were considered inoperable in all the patients. Using a flexible 20 Fr. intubator and assisted by endoscopy and fluoroscopy, 3 uncovered stents, 7 fully covered stents and 62 partially covered stents were inserted.

RESULTS:

A stent was inserted in 67 of the 72 patients (93%) and no patient showed any duodenal perforation nor needed surgery. As to the symptoms, of the 12 patients who did not tolerate any type of oral treatment, 10 improved after the duodenal stents were introduced. Stent migration was observed in 6 cases, 4 of these with fully covered stents. In these cases, the stents were removed by endoscopy and then replaced by a partially covered stent. Tumor colonization was observed in five cases, two of them with the uncovered stents initially used. Out of the 62 procedures with partially covered stents, migration was observed in two cases and only two stents were colonized by the tumor. Patients died between 1 and 96 weeks after introducing the stents (average survival was 20.7 weeks).

CONCLUSIONS:

Peroral placement of nitinol stents is an effective and easy method of mitigation for most patients with malignant gastro-duodenal obstructions. Migration of fully covered stents and tumor colonization of uncovered stents are important limitations, which can be avoided by using partially covered stents.

• Authors: Rodrigo Castaño Llano, Oscar Alvarez Barrera, Jorge Lopera, Mario H Ruiz Vélez, Fabian Juliao Baños, Eugenio Sanín Fonnegra, Faruk Erebrie
• Journal: Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru (Rev Gastroenterol Peru) 2006 Jul-Sep Vol. 26 Issue 3 Pg. 233-41 ISSN: 1022-5129 [Print] Peru
• Vernacular Title: El uso de Prótesis de Nitinol parcialmente cubierto en la Obstrucción Gastroduodenal maligna.
• PMID: 17053819 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Alloys
• Coated Materials, Biocompatible
• nitinol

Topics

• Adult
• Aged
• Aged, 80 and over
• Alloys (therapeutic use)
• Coated Materials, Biocompatible (therapeutic use)
• Digestive System Surgical Procedures (methods)
• Duodenal Neoplasms (diagnostic imaging, surgery)
• Duodenoscopy
• Female
• Gastric Outlet Obstruction (diagnostic imaging, surgery)
• Humans
• Male
• Middle Aged
• Palliative Care
• Postoperative Complications
• Prospective Studies
• Radiography
• Stents
• Stomach Neoplasms (diagnostic imaging, surgery)
• Treatment Outcome