[Late secondary syphilis with ulceration of the tongue during HIV coinfection: case report].

With the continuing rise of syphilis incidence, late stages and atypical courses with HIV-coinfection can be expected. A 45 year old HIV infected male presented with an unusual manifestation of late secondary syphilis on the tongue, which was first diagnosed as a squamous cell carcinoma but cleared after therapy with penicillin. He also exhibited psoriasiform and annular lesions on the trunk and hyperkeratotic papules on the palms of the hand and soles of the feet. A TPHA test was negative due to a prozone phenomenon. With this case, we would like to emphasize the formerly well known relationship between the lesions of tertiary syphilis on the tongue and development of secondary carcinoma.
AuthorsP Spornraft-Ragaller, U Boashie, K Friedrich, U Lehmann, M Meurer
JournalDer Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete (Hautarzt) Vol. 57 Issue 11 Pg. 1005-8 (Nov 2006) ISSN: 0017-8470 [Print] Germany
Vernacular TitleSpätsekundäre Syphilis mit Ulzeration der Zunge bei HIV-Koinfektion: Fallbericht.
PMID17051406 (Publication Type: Case Reports, English Abstract, Journal Article)
Chemical References
  • Anti-Bacterial Agents
  • Anti-Retroviral Agents
  • Penicillin G
  • Anti-Bacterial Agents (therapeutic use)
  • Anti-Retroviral Agents (administration & dosage, therapeutic use)
  • Biopsy
  • Carcinoma, Squamous Cell (diagnosis)
  • Diagnosis, Differential
  • False Negative Reactions
  • Foot Dermatoses (diagnosis, etiology)
  • HIV Infections (complications, drug therapy)
  • Hand Dermatoses (diagnosis, etiology)
  • Humans
  • Male
  • Middle Aged
  • Penicillin G (therapeutic use)
  • Syphilis (complications)
  • Syphilis Serodiagnosis
  • Syphilis, Cutaneous (complications, diagnosis, pathology)
  • Tongue (pathology)
  • Tongue Diseases (diagnosis, drug therapy, etiology, pathology)
  • Tongue Neoplasms (diagnosis)
  • Treatment Outcome

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