Abstract | BACKGROUND: METHODS: A retrospective chart review of 760 intracarotid amobarbital and methohexital tests was performed to determine the frequency of seizures associated with preoperative intracarotid barbiturate testing for language and memory lateralization. RESULTS: Sixteen patients (2.1%) who had seizures were found. In 3 patients, seizures occurred prior to barbiturate injection, and in 13, following barbiturate injection. After injection of amobarbital, 4 of 538 patients (0.7%) had a seizure. Nine of 222 patients had a seizure after methohexital injection (4.1%) (P=0.001). CONCLUSION:
|
Authors | Tobias Loddenkemper, Gabriel Möddel, Stephan U Schuele, Elaine Wyllie, Harold H Morris 3rd |
Journal | Epilepsy & behavior : E&B
(Epilepsy Behav)
Vol. 10
Issue 1
Pg. 49-54
(Feb 2007)
ISSN: 1525-5069 [Electronic] United States |
PMID | 17049312
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
|
Chemical References |
- Barbiturates
- Hypnotics and Sedatives
- Methohexital
- Amobarbital
- barbituric acid
|
Topics |
- Adolescent
- Adult
- Amobarbital
(administration & dosage, adverse effects)
- Barbiturates
- Electroencephalography
(methods)
- Female
- Humans
- Hypnotics and Sedatives
(administration & dosage, adverse effects)
- Injections, Intra-Arterial
- Language
- Male
- Memory
(drug effects)
- Methohexital
(administration & dosage, adverse effects)
- Retrospective Studies
- Seizures
(chemically induced, physiopathology)
|