[Affection of Bushen Shengjing pill on NO and NOS in testicle and ante-oxidization of rat with spermatogenic cell injury].

Abstract

OBJECTIVE:

Discuss the functional mechanism of treating male infertility with Bushen Shengjing pill (BS).

METHOD:

Fill the SD rat with adenine so as to injure the germ cell which will produce the model rat with kidney yang deficiency. Measure the activity of SOD and NOS, the amount of NO and MDA in the testicle.

RESULT:

BS can promote the activity of SOD, reduce the activity of NOS and the amount of NO and MDA.

CONCLUSION:

BS has the function of protecting the germ cell which is closely related to the function that the pill can promote the activity of SOD, reduce the activity of NOS and the amount of NO and MDA.

• Authors: A-min Yang, Yue-qing Li, Hai-song Li, Chong-shun Song, Ying Ren, Jun-xiang Yin
• Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica (Zhongguo Zhong Yao Za Zhi) Vol. 31 Issue 11 Pg. 904-6 (Jun 2006) ISSN: 1001-5302 [Print] China
• PMID: 17048630 (Publication Type: English Abstract, Journal Article)

Chemical References

• Drug Combinations
• Drugs, Chinese Herbal
• Fertility Agents, Male
• Nitric Oxide
• Malondialdehyde
• Nitric Oxide Synthase
• Superoxide Dismutase
• Adenine

Topics

• Adenine
• Animals
• Drug Combinations
• Drugs, Chinese Herbal (isolation & purification, pharmacology)
• Fertility Agents, Male (pharmacology)
• Kidney Diseases (chemically induced, metabolism)
• Male
• Malondialdehyde (metabolism)
• Nitric Oxide (metabolism)
• Nitric Oxide Synthase (metabolism)
• Plants, Medicinal (chemistry)
• Random Allocation
• Rats
• Rats, Sprague-Dawley
• Spermatogenesis (drug effects)
• Superoxide Dismutase (metabolism)
• Testis (metabolism)
• Yang Deficiency (chemically induced, metabolism)