Abstract | BACKGROUND:
5-Aminosalicylic acid (5-ASA)-containing drugs are the mainstay of therapy in inflammatory bowel disease, but adverse reactions to these medications are relatively common. Because there may be a lack of cross-reactivity among the various 5-ASA formulations, treatment with alternative preparations is sometimes possible even after an apparent allergic reaction to a 5-ASA product. OBJECTIVE: To describe a patient with a possible allergy to 2 different 5-ASA drugs who tolerated a third. METHODS: RESULTS: CONCLUSIONS: Adverse reactions to 1 or more 5-ASA medications do not necessarily preclude the use of others in the same class. A treatment algorithm for patients with adverse reactions to 5-ASA is outlined based on the case report and review of the literature.
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Authors | Shiang-Ju Kung, Cuckoo Choudhary, Stephen J McGeady, John R Cohn |
Journal | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology
(Ann Allergy Asthma Immunol)
Vol. 97
Issue 3
Pg. 284-7
(Sep 2006)
ISSN: 1081-1206 [Print] United States |
PMID | 17042131
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Anti-Inflammatory Agents, Non-Steroidal
- Immunosuppressive Agents
- Phenylhydrazines
- Mesalamine
- Mercaptopurine
- balsalazide
- Prednisone
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Topics |
- Adult
- Anti-Inflammatory Agents, Non-Steroidal
(immunology)
- Crohn Disease
(drug therapy)
- Cross Reactions
- Drug Hypersensitivity
(immunology)
- Exanthema
(chemically induced, drug therapy)
- Herpes Simplex
(drug therapy, etiology)
- Humans
- Immunosuppressive Agents
(therapeutic use)
- Male
- Mercaptopurine
(therapeutic use)
- Mesalamine
(adverse effects, immunology, therapeutic use)
- Phenylhydrazines
(therapeutic use)
- Prednisone
(therapeutic use)
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