[The effect of shanzha xiaozhi capsule on the blood lipid and the function of endothelial cells in patients with dislipide mia].

Abstract

OBJECTIVE:

To explore the Mechanism of Shanzha xiaozhi Capsule improving the functions of endonthelial cells in patients with dislipide mia.

METHODS:

To measurate the blood lipid and the levels of plasma Endothelin (ET) and nitrodi oxide (NO) in 30 patients with dislipide mia before and after taking the Shanzha xiaozhi Capsule, and there were 10 normal persons in control group, which were measured the blood lipid and the levels of ET and NO only one time.

RESULTS:

After treatment with Shanzha xiaozhi Capsule, the levels of triglyceride (TG), total cholesterol (TC), low density lipoprotein cholestero (LDL-C), ET were markedly reduced (P < 0.05), and the levels of NO were obviously elevated (P < 0.05).

CONCLUSION:

Shanzha xiaozhi Capsule can reduce blood lipid level and the plasma ET levels, increase the NO levels and the protection to the functions of endothelial cells which might be involved in the mechanisms of against atherosclerosis.

• Authors: Hua-yun Zhao, Wen-hui Wang
• Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials (Zhong Yao Cai) Vol. 29 Issue 6 Pg. 629-31 (Jun 2006) ISSN: 1001-4454 [Print] China
• PMID: 17039887 (Publication Type: English Abstract, Journal Article)

Chemical References

• Capsules
• Cholesterol, LDL
• Drugs, Chinese Herbal
• Endothelins
• Hypolipidemic Agents
• Lipids
• Triglycerides
• Nitric Oxide
• Cholesterol

Topics

• Atherosclerosis (prevention & control)
• Capsules
• Cholesterol (blood)
• Cholesterol, LDL (blood)
• Drugs, Chinese Herbal (pharmacology, therapeutic use)
• Endothelins (blood)
• Endothelium, Vascular (drug effects, physiopathology)
• Humans
• Hyperlipidemias (blood, drug therapy)
• Hypolipidemic Agents (pharmacology, therapeutic use)
• Lipids (blood)
• Nitric Oxide (blood)
• Phytotherapy
• Plants, Medicinal (chemistry)
• Triglycerides (blood)