Allergic contact dermatitis to copolymers in cosmetics--case report and review of the literature.

Copolymers or heteropolymers are large molecules with high molecular weights (>1000 D). They have been underestimated for a long time as to their sensitizing capacities. Allergic contact dermatitis to 6 copolymers in cosmetics and 1 in a medical dressing has been described; however, the nature of the hapten is still unknown. We report a case of allergic contact dermatitis to polyvinylpyrrolidone (PVP)/hexadecene copolymer in a purple-colored lipstick and review the literature on allergic contact dermatitis to 7 copolymers: PVP/hexadecene, PVP/eicosene, PVP/1-triacontene, methoxy polyethyleneglycol (PEG)-22/dodecyl glycols, methoxy PEG-17/dodecyl glycols, phthalic anhydride/trimellitic anhydride/glycols, and polyvinyl methyl/maleic acid anhydride.
AuthorsSarah Quartier, Marjan Garmyn, Sophie Becart, An Goossens
JournalContact dermatitis (Contact Dermatitis) Vol. 55 Issue 5 Pg. 257-67 (Nov 2006) ISSN: 0105-1873 [Print] Denmark
PMID17026690 (Publication Type: Case Reports, Journal Article, Review)
Chemical References
  • Allergens
  • Cosmetics
  • Maleic Anhydrides
  • Pharmaceutic Aids
  • Phthalic Anhydrides
  • Polymers
  • Polyvinyls
  • Surface-Active Agents
  • methoxy polyethylene glycol amine
  • Polyethylene Glycols
  • trimellitic anhydride
  • Povidone
  • phthalic anhydride
  • Adult
  • Allergens (adverse effects)
  • Cosmetics (adverse effects, chemistry)
  • Dermatitis, Allergic Contact (etiology)
  • Humans
  • Male
  • Maleic Anhydrides (adverse effects, analysis)
  • Pharmaceutic Aids (adverse effects, analysis)
  • Phthalic Anhydrides (adverse effects, analysis)
  • Polyethylene Glycols (adverse effects, analysis)
  • Polymers (adverse effects, analysis)
  • Polyvinyls (adverse effects, analysis)
  • Povidone (adverse effects, analogs & derivatives, analysis, chemistry)
  • Surface-Active Agents (adverse effects, analysis)

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